Des-γ-carboxy-prothrombin
WebNov 15, 2024 · Des-γ-carboxy-prothrombin (DCP) is an abnormal prothrombin in which one or more glutamic acid residues of the Gla domain are not fully carboxylated to gamma-carboxylated glutamate (Gla) in its … WebOct 4, 2024 · To explore the diagnostic efficacy of des-gamma-carboxy prothrombin (DCP) in hepatitis B virus- (HBV-) related hepatocellular carcinoma (HCC). A retrospective study of 459 cases from June 2016 to March 2024 was …
Des-γ-carboxy-prothrombin
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WebDes-γ-carboxy prothrombin (DCP), an aberrant prothrombin produced by hepatocellular carcinoma (HCC) cells, has been shown to be associated with the … WebDes-γ-carboxy (abnormal) prothrombin and hepatocellular carcinoma: A critical review. Ilene C. Weitz, Ilene C. Weitz. Division of Hematology and Oncology, Department of Medicine, Sepulveda Veterans Administration Hospital-San Fernando Valley Medical Center and the UCLA School of Medicine, Los Angeles.
WebDes-gamma-carboxy prothrombin (DCP), also known as PIVKA-II, is a form of factor II produced in the absence of vitamin K, and is therefore an unmodified form of the protein. … WebNov 20, 2000 · Des-γ-carboxy prothrombin (DCP) is an established marker for hepatocellular carcinoma (HCC), but the conventional enzyme immunoassay (EIA) kit lacks adequate sensitivity. Thus, a revised EIA kit with increased sensitivity has been developed. In this kit, the sensitivity has increased while high specificity to HCC has been maintained.
WebOct 31, 2000 · Serum concentrations of des-γ-carboxy prothrombin (DCP) from 91 patients with hepatocellular carcinoma (HCC) and 57 with cirrhosis (LC) are shown. There is a statistically significant difference between the serum concentrations of DCP in HCC (48.3 ± 24.3, mean ± standard deviation) and those in cirrhosis (20.3 ± 10.3), as determined by … WebDes-gamma-carboxy prothrombin (DCP), also known as the protein induced by vitamin K absence or antagonist II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. DCP is a nonfunctional prothrombin resulting from a lack of carboxylation …
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WebSaito M, Seo Y, Yano Y, Miki A, Yoshida M, Azuma T. A high value of serum des-γ-carboxy prothrombin before hepatocellular carcinoma treatment can be associated with long-term liver dysfunction after treatment. J. Gastroenterol. 2012; 47 (10):1134–1142. doi: 10.1007/s00535-012-0577-0. [Google Scholar] in which two ways can sedimentary rocks formWebDec 4, 2003 · Des-γ-carboxy prothrombin (DCP) is useful as a marker of hepatocellular carcinoma (HCC). However, because of its low sensitivity, DCP is not suitable for the … in which type of cell is dna circularWebNov 29, 2015 · Determining the serum des-γ-carboxy-prothrombin (DCP) level is of great importance for the diagnosis of primary hepatocellular carcinoma (PHC). Although several studies have investigated the accuracy of diagnostic DCP tests for PHC, the results have been inconsistent. The aim of this study was to systematically evaluate DCP as a … in which type of raid the data is mirroredWebProtein induced by vitamin K or antagonist-II (PIVKA-II; also known as des-γ-carboxy prothrombin [DCP]) has been identified as a promising biomarker with utility in the surveillance, diagnosis, and management of … in which type of cells meiosis occursWebProtein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the … on off hire port denmarkWebNov 25, 2024 · This prospective study investigated the impact of cabozantinib exposure on proteinuria and muscle toxicity, in a cohort of 14 Japanese patients with unresectable hepatocellular carcinoma (uHCC). We measured the trough concentration of cabozantinib (Ctrough) weekly for 6 weeks after starting treatment. Although the initial dose was less … in which type of soil jute growWebBackground: The role of des-γ-carboxy prothrombin (DCP) in patients undergoing radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) needs to be clarified. … in which type of cell does mitosis take place